Donate Deakin

What is the HARMON-E study?

The HARMON-E trial is a group-based, telehealth clinical trial designed to support positive lifestyle changes to improve mental health for adults who are experiencing depression or bipolar disorder. HARMON-E is based on well-established evidence for lifestyle interventions as effective strategies for improving depressive symptoms and common associated physical health conditions.

How are we doing this study?

We are recruiting 378 people (18+) from across Australia to participate in this study. Participants are randomly allocated into one of two programs: 1) led by allied health professionals and 2) led by clinical psychologists. Each program is 8 weeks long and we will measure changes in depressive symptoms over this period and compare them between the two groups.

Participants are asked to: 

  • Join one 30-minute one-on-one introductory session with their interventionist via video call (Zoom)
  • Join six 90-minute mental health sessions via video call with a group of up to 7 other people (the same group each time)
  • Answer questions in 5 one-on-one interviews over zoom about your health and wellbeing
  • Make 2 visits to your local pathology to have a blood test and your height and weight measured
  • Collect 2 stool samples at home

What are we hoping to find? The trial aims to determine whether a lifestyle-based approach to mental health care is as good as psychotherapy for reducing symptoms of depression.

Interested in participating?

If you are interested in participating you can complete a quick, 5 minute online prescreening survey to see if you may be eligible. Click here to check your eligibility.

If you would like to receive more information about the study, please contact us at or submit your details using the form below.

This trial is supported by a 2020 MRFF Million Minds Mission MHR grant (Mental Health Australia General Clinical Trial Network – MAGNET: GNT2006296).

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