Dr Wolfgang Marx is a postdoctoral research fellow and Head of the Nutraceutical Research stream at the Food & Mood Centre. Wolfgang is also an Accredited Practising Dietitian and received his PhD from Bond University where he investigated the use of a ginger-derived polyphenols for chemotherapy-induced nausea and fatigue. Wolfgang’s current research program covers a broad range of projects involving the use nutraceuticals for mental health, fatigue, and cognition. Of particular interest is the role of polyphenols – compounds found abundantly in spices, fruits, and vegetables – in mental and brain health. This research program uses a bench-to-beside approach, covering a variety of study designs including clinical trials, meta-analyses, epidemiology, and mechanistic studies.
Wolfgang is leading the following research projects:
Researching the Effectiveness of a nutraceuticaL Intervention for multiplE sclerosis-related Fatigue (RELIEF) Trial
An NHMRC-funded multicentre clinical trial that is investigating the role of a combined nutraceutical intervention on fatigue and depression in 150 people with multiple sclerosis. As part of this trial, Wolfgang is also investigating the role of the microbiome and the kynurenine pathway on treatment response.
Investigating the role of dietary polyphenol intake on cognition, fatigue, and depression
Using well-characterised datasets including the Ausimmune observational study and the UKBiobank, Dr Marx is investigating the role of dietary polyphenols on brain health.
Systematic review and meta-analyses of nutraceutical interventions
Wolfgang has an ongoing research program that provides meta-analysis and systematic literature reviews on novel nutraceutical and bioactive foods and their role in depression and cognition.
Research areas and skills: polyphenol and nutraceutical research; cognition; meta-analyses and systematic literature review; mechanisms of action; metabolomics